| No | Nama Pemain | Klub | Gol |
| 1 | Lionel Messi | Barcelona | 27 |
| 2 | Radamel Falcao | Atletico Madrid | 17 |
| 3 | Cristiano Ronaldo | Real Madrid | 16 |
| 4 | Aritz Aduriz | Athletic Bilbao | 11 |
| Roberto Soldado | Valencia | 11 | |
| 6 | Ruben Castro | Real Betis | 10 |
| 7 | Piti | Rayo Vallecano | 9 |
| 8 | Helder Postiga | Real Zaragoza | 8 |
| Oscar Gonzalez | Real Valladolid | 8 | |
| Iago Aspas | Celta Vigo | 8 | |
| Alvaro Negredo | Sevilla FC | 8 | |
| 12 | Gonzalo Higuain | Real Madrid | 7 |
| Carlos Vela | Real Sociedad | 7 | |
| Tomer Hemed | Mallorca | 7 | |
| 15 | Obafemi Martins | Levante | 6 |
| Riki | Deportivo La Coruna | 6 | |
| Manucho | Real Valladolid | 6 | |
| Jorge Molina | Real Betis | 6 | |
| Victor Casadesus | Mallorca | 6 | |
| Leo | Rayo Vallecano | 6 | |
| 21 | Roque Santa Cruz | Malaga | 5 |
| Xavi | Barcelona | 5 | |
| Javier Saviola | Malaga | 5 | |
| David Villa | Barcelona | 5 | |
| Cesc Fabregas | Barcelona | 5 | |
| Verdu | Espanyol | 5 | |
| Karim Benzema | Real Madrid | 5 | |
| Adriano | Barcelona | 5 | |
| Patrick Ebert | Real Valladolid | 5 | |
| Apono | Real Zaragoza | 5 | |
| Pizzi | Deportivo La Coruna | 5 |
